Abstract
s / Pancreatology 586 Patients and methods: 117 consecutive patients underwent a DP at the University hospital in Heidelberg between 05/2009 and 09/2010. A coverage procedure was performed in 73 of these patients. All patients were recorded prospectively, and the clinical course was evaluated focusing on the occurrence of pancreatic fistula (ISGPF-definition). Treatment cost analysis was performed. Results: The rate of clinically relevant pancreatic fistulas (type B and C) was decreased in patients with coverage compared to the standard controls (type B: 7% vs. 9%; type C: 7% vs. 25%; p<0.002). Patients with a coverage procedure had a lesser (p<0.02) hospital duration of stay, and treatment costs were less (p<0.001) compared to patients without coverage. Conclusion: Coverage of the pancreatic remnant after DP decreases the rate of clinically relevant pancreatic fistulas, duration of stay, and treatment costs. A randomized trial is needed to verify these results.
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