Radiofrequency Ablation for Cancer: Current Indications, Techniques and Outcomes

Abstract

Radiofrequency Ablation for Cancer is an all-inclusive textbook solely devoted to the therapeutic modality, radiofrequency ablation (RFA), a popular and ever-increasing technique being applied in the treatment of solid tumors. The editors have assembled a cadre of recognized experts in their respective fields with extensive experience in the use of this therapeutic technique. Together, the editors and contributing authors have compiled an important overview of the state of the art for RFA, which is a must read for anyone currently using or contemplating incorporating this approach into their therapeutic armamentarium. The main target audience is comprised of those individuals who would use this innovative tool or who are involved in the management of patients treated by this modality, including surgeons, oncologists, and interventional radiologists. It will also prove useful for residents and fellows who want an understanding of the biologic basis and therapeutic implications of this procedure. The book is divided into 4 major sections. The first addresses the principles and generalized technique of RFA. The section is dedicated to RFA of both primary and secondary liver malignancies, those tumors that comprise the most common indication for this technique. The chapters in this section detail the current indications and techniques of ablation for hepatic metastasis and hepatocellular carcinoma. The authors provide scientifically derived results supporting the use of RFA but refreshingly point out the shortcomings of the procedure and the limited nature of the data serving as a foundation for its increased use in today's oncology care. Chapters are devoted to combined modality RFA with interarterial chemotherapy and the decision-making process regarding the use of resection versus RFA in the treatment of hepatic malignancy. The technique of laparoscopic RFA for hepatic tumors is also addressed. Finally, this section is completed by a thorough review of the complications associated with the technique and the lessons learned to safely apply this treatment device for liver tumors. The third section provides single chapter, state-of-the-art reviews on the use for RFA to solid tumors at various sites including breast, bone, kidney, lung, and thyroid. All of these chapters provide a concise and fair evaluation of the technique in the various settings described. The last section is dedicated to the role of imaging for appropriate application and follow-up of the technique. The book is well organized and easy to read. My only minor criticism is that the principles and technique of RFA, which are well outlined in the first chapter of the book, are frequently repeated in various chapters throughout the text. The book is peppered with wonderful, high-quality illustrations and photographs that complement the text well. Although the textbook does not replace the need for hands-on training and experience, it is a welcomed and necessary addition to the literature that provides a genuine summation of the art and science of this rapidly adopted and fashionable treatment modality.