Abstract

The escalation in application of cyclotron produced radionuclides particularly directed toward positron emission tomography has placed increased demands upon cyclotron facilities to provide a variety of radiopharmaceutical agents in a timely manner with efficient utilization of space and human resources. A unique approach to this challenge has been developed which adapts currently available chemical equipment and “in-house” software packages. The central component of our synthetic unit is a commercially available autosampling injection device that has been modified to allow a combination of chemical manipulations to be performed. The compact unit efficiently utilized restricted “hot cell” space and is readily serviced. The system is currently in operation for the radiopharmaceutical preparation of “no carrier added” 18F labeled 2-fluoro-2-deoxy-D-glucose. A detailed description of the radiochemical unit and its capabilities will be presented.

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