Abstract
The adhesive tumour cell culture system (ATCCS) has been proposed as a predictive test for radiosensitivity because of its short culture period, selective growth of tumour cells and because it is thought to yield a result which reflects the clonogenic cell response. We have compared the radiosensitivity of a range of human tumour cell lines using the ATCCS and clonogenic survival. We found that the optical method of assessing cell number and radiosensitivity gave good agreement with clonogenic response at 2 Gy, although the ATCCS response showed unusually high radioresistance at high doses.
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