Radioactivity and annual effective dose in some types of drug

Ali Dawoud Salloum

doi:10.30723/ijp.v15i34.123

Abstract

The aim of this research is to know danger of radioactive isotopesthat are found in samples of drugs traded in Iraqi markets. Thesamples are Iraqi Amoxicillin, English Amoxicillin, UAEAmoxicillin, Indian Amoxicillin, Iraqi Paracetamol, EnglishParacetamol, UAE Paracetamol and Indian Paracetamol. By highpurity germanium the activity of the following isotopes 40K, 214Pb,228Ac and 137Cs is measured and the specific activity was used tocalculate the annual effective dose. Then the calculated annualeffective dose values are compared with the allowable annualeffective dose values of each part of digestive channel. This researchconcluded that the measured annual effective dose values are notdangerous.

Highlights

The exposure of human existence to radiation from things that is inevitable because all that is around us contain radioactive nuclide in different rates
In order to know the risk of radioactive isotopes in drug samples, the annual effective dose must be measured and compared with the allowed dose for each part of human body
The annual effective dose was calculated from equation where is radiation weighting factor which represents the number by which the absorbed dose in a tissue or organ is multiplied to reflect biological effectiveness of the radiation in inducing stochastic effects at low doses

Summary

Introduction

The exposure of human existence to radiation from things that is inevitable because all that is around us contain radioactive nuclide in different rates. The radioactive sources are divided to natural and artificial sources [1] It is about 80% from human exposure comes from natural sources [2, 3]. The artificial radioactive sources come from human activities, weapons and nuclear accidents like Chernobyl power station accident in 1986 [8, 9]. The samples are antiinflammatory and relievers drugs because they are of the most drugs commonly used It has been selected Amoxicillin and Paracetamol from four origins which Iraqi, English, Indian and United Arab Emirates, because they are the most actively traded in the Iraqi market if they compare with others origins. Since the less mass which can detector tests it is 9 g, the mass must be placed in detector is 9 g or more

Results and discussion

Specific Sample In take per Annual Effective

Sample In take per Annual Effective

Conclusions