Radical Scavenging Activity and Antibacterial Effect of Three Cyclamen L. Tuber Extracts on Some Fish Pathogens

Cennet Özay,Gülşen Uluköy,Zeynep Sayin,Ramazan Mammadov

doi:10.19113/sdufbed.65047

Cennet Özay, Gülşen Uluköy + Show 2 more

Open Access

https://doi.org/10.19113/sdufbed.65047

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Abstract

Cyclamen L. is a member of Primulaceae family, a geophyte, which have been utilized for their biological activities in folk medicine. The aim of this study is to investigate the antibacterial activity of three Cyclamen species on some fish pathogens as well as their radical scavenging activity potentials. C. cilicium Boiss. & Heldr., C. pseudibericum Hildebr. and C. hederifolium Aiton were collected from different regions in Turkey. Cyclamen tubers were extracted in ethanol and then DPPH, ABTS and NO methods were utilized for the assurance of radical scavenging activities of the extracts. Antibacterial activity of the extracts were determined in vitro against five bacterial fish pathogens, namely, Vagococcus salmoninarum, Staphylococcus epidermidis, Lactococcus garvieae, Vibrio anguillarum and Yersinia ruckeri . All the tested tuber extracts exhibited moderate antibacterial activity against four bacteria and the radical scavenging activity in the order of potency: C. cilicium > C. pseudibericum > C. hederifolium . In conclusion, this study showed that the Cyclamen species have moderate antibacterial activity against fish pathogenic bacteria except V. anguillarum .

Highlights

The diminishing of fish from natural resources and expanding need for food are the two principle factors for the demand of developing aquaculture sector [1].To be able to meet the consumers demand for fish, aquaculture has been continued to spread out very rapidly
The results showed that all the Cyclamen tuber extracts exhibited moderate antibacterial activity against all tested bacteria except V. anguillarum
They have important metabolites which could be discovered as a candidate for the development of new chemotherapeutics agents. Their active secondary metabolites are not definitely required for the normal plant growth but responsible for a lot of bioactive compounds used in health of organisms

Summary

Introduction

The diminishing of fish from natural resources and expanding need for food are the two principle factors for the demand of developing aquaculture sector [1].To be able to meet the consumers demand for fish, aquaculture has been continued to spread out very rapidly. The using of antibiotics for the treatment of diseases generates some reactions such as; toxic effect onto fish and the residue deposition into the aquatic environment. These residues could accumulate and influence health of organisms [6]. It was expressed that some bacterial pathogens have gained antibacterial resistance against the antibiotics [7]. These issues have urged to look for other antibacterial substances that can be applicable as much as a drug [8]. Natural products are of great interest as a promising source to control disease problems in aquaculture [12]

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