Abstract

This chapter will present an overview of two radiation-based medical imaging techniques using radiopharmaceuticals used in nuclear medicine/molecular imaging, namely, single-photon emission computed tomography (SPECT) and positron emission tomography (PET). The relative merits in terms of radiation sensitivity and image resolution of SPECT and PET will be compared to the main conventional radiologic modalities that are computed tomography (CT) and magnetic resonance (MR) imaging. Differences in terms of temporal resolution will also be outlined, as well as the other similarities and dissimilarities of these two techniques, including their latest and upcoming multimodality combination. The main clinical applications are briefly described and examples of specific SPECT and PET radiopharmaceuticals are listed. SPECT and PET imaging will be then further detailed in the two subsequent chapters describing in greater depth the basics and future trends of each technique (see > Chaps. , “SPECT Imaging: Basics and New Trends” and > , “PET Imaging: Basics and New Trends”).

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