Abstract

Radiation therapy to the pelvis may induce complicated bone and soft-tissue pathology especially in osteopenic patients. These benign disorders can show abnormal F-18 FDG uptake on PET scans and may be misinterpreted as recurrent or metastatic lesions. We report an elderly osteopenic patient with postoperative uterine cancer, who showed abnormal FDG uptake in a hematoma associated with a pubic fracture and in a sacral insufficiency fracture after postoperative adjuvant radiation therapy, with coexisting abnormal uptake in a recurrent metastatic lymph node. Metabolic-morphologic correlation on PET-CT scan could characterize these benign disorders and led to the correct diagnosis. The PET-CT scan appears useful to avoid misinterpretation for radiation-induced, complicated pelvic bone and soft-tissue disorders showing abnormal FDG uptake.

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