Abstract
The authors analyzed treatment results in 71 cases of Wilms's tumor. The abdominal control rate was higher in 42 patients receiving postoperative radiotherapy (85.5%) than in 6 patients not receiving such therapy (1/6). In patients treated by nephrectomy and postoperative radiation, the addition of chemotherapy improved survival (78.2 VS. 30%). Pulmonary metastasis did not necessarily denote a hopeless situation since a significant number of patients could be salvaged by concurrent radiotherapy and chemotherapy; higher control rates were achieved with total than with less-than-total thoracic irradiation. Relatively low-dose irradiation appeared sufficient in both abdominal and thoracic radiotherapy if chemotherapy was given concurrently.
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