Abstract
The rate of DNA repair, as measured by “unscheduled” incorporation of 3H-thymidine following ultraviolet light irradiation, increases approx. 50% during stimulation of lymphocytes by phytohemagglutinin. This increase is parallell in time with a rise in DNA polymerase activity which occurs during stimulation, but is almost two orders of magnitude lower than the increase in enzyme activity. The rate of DNA repair in granulocytes is five times lower than in unstimulated lymphocytes. The possible involvement of DNA polymerase in DNA repair replication is discussed.
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