Abstract
Clinical and necropsy findings are described in a 42-year-old man who received mediastinal irradiation (about 40 Gy) for Hodgkin's disease when he was 24 years old. He subsequently developed virtually every cardiovascular manifestation of radiation heart disease, including constrictive pericardial disease, complete occlusion of the ostium of a coronary artery, severe narrowing of the right coronary artery and of both carotid arteries, complete heart block (infranodal), hemodynamically confirmed aortic valve stenosis, and transmural right ventricular infarction.
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