Abstract
Radiation-Induced Breast Angiosarcoma After Breast Cancer: A Case Report
Highlights
Breast sarcomas are heterogeneous tumors that arise from mesenchymal cells, from the mammary connective tissue
We present a case of radio-induced breast angiosarcoma after breast conserving surgery and adjuvant Radiation Therapy (RT) in a patient with breast cancers (BC); an infrequent entity with difficult diagnosis and poor prognosis
The average age for secondary angiosarcomas is generally greater than 60 years [6,11,12] and they appear in patients who have received treatment for BC
Summary
Breast sarcomas are heterogeneous tumors that arise from mesenchymal cells, from the mammary connective tissue. Breast angiosarcoma is an aggressive subtype, with rapid proliferation and infiltration of surrounding tissues; generally associated with poor prognosis. Based on their etiology, it can be classified as primary (de novo) and secondary (related to BC treatment: after radiation therapy -RT-, or due to lymphedema in the arm or breast/chest wall after surgical treatment) [2,3]. We present a case of radio-induced breast angiosarcoma after breast conserving surgery and adjuvant RT in a patient with BC; an infrequent entity with difficult diagnosis and poor prognosis. Diagnosed several years ago with coronary insufficiency, with episodes of angina pectoris and arterial hypertension She consulted for a nodule in the left breast of two months of evolution. Our patient died 11 months after the initial diagnosis of angiosarcoma
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