Abstract
Angiosarcomas are malignant mesenchymal tumours that develop from the endothelium of a blood vessel. It is an uncommon cancer that occurs among men and women, more often among older adults and usually in the skin, soft tissue, breast, or liver. Angiosarcoma is a rare but well recognised complication after radiation therapy. Most post radiation angiosarcomas are seen in the breast and very few cases of angiosarcoma have been reported following radiotherapy for cervical cancer.We report one such case of post radiation angiosarcoma which developed years after radiation therapy for carcinoma cervix.
Highlights
Case historyA 56 year old female was diagnosed with focally keratinising grade 3 squamous cell carcinoma for which she had undergone hysterectomy elsewhere and was referred to our institute for radiotherapy
Angiosarcomas are malignant mesenchymal tumours that develop from the endothelium of a blood vessel
The tumour cells were negative for panCK, EMA, ER, PR, p16, p40, p63, HMB45 and S100 which excluded the diagnosis of metastatic squamous cell carcinoma, endometrial stromal sarcoma and malignant melanoma
Summary
A 56 year old female was diagnosed with focally keratinising grade 3 squamous cell carcinoma for which she had undergone hysterectomy elsewhere and was referred to our institute for radiotherapy. She underwent external beam radiotherapy of the pelvis (Telecobalt, total 3771 cGy in 25 fractions) and intravaginal brachytherapy (30 Gy). After a latency period of 6 years the patient presented with a lower abdominal wall nodule in the midline
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
