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Abstract
1817 Objectives The prevalence of left ventricular mechanical dyssynchrony (LVMD) in stable angina pectoris (AP) has not been fully clarified. The aim of this study was to assess the presence and severity of LVMD in stable AP. Methods A total of 201 patients (age 69 ± 11, 137 males) with suspected ischemic heart disease underwent stress/rest gated myocardial perfusion SPECT (GMPS). For the evaluation of LVMD, histogram bandwidth (HBW) and phase standard deviation (PSD) were determined by GMPS using phase analysis. LVMD at stress and rest were compared among three groups: 103 normal patients (NG) [summed stress score (SSS) 50 %], 54 patients with ischemia (IG) [SSS > 3, summed difference score (SDS) > 1, and summed rest score (SRS) 3 and SDS Results The measured LVMD parameters (HBW and PSD) in NG, IG, and pMIG are summarized in the figure. At stress, both HBW and PSD in IG were significantly greater than those in NG (p Conclusions In patients with stable AP, LVMD was demonstrated to be enhancement at stress, and was found to be detectable equally well with prior MI
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