Abstract
A track structure model is presented which describes the energy deposition of ions, electrons, gamma rays and X rays in liquid water. The model starts from first physical principles, includes the single excitation spectrum of liquid water and takes into account all particles involved in the energy deposition process. This model is used to calculate DNA single strand breaks and double strand breaks and a good fit has been found for X rays and various ions. The model is also used to calculate the linear coefficient of the dose survival curve for two cell types, assuming that DNA double strand breaks are the crucial lesions. In this case a good description of the behaviour of the linear dose term was found for various ions, gamma rays and X rays of 300 keV, 1.5 keV and 0.3 keV, assuming one type of interaction of the water radicals with DNA to produce DNA double strand breaks. The results support the hypothesis that one type of lesion is responsible for the low dose component of cell lethality.
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