Abstract
Background T2 mapping through variation of the T2 preparation (T2Prep) duration has been increasingly used to robustly detect and quantify cardiac edema (Giri et al., JCardiovMagnReson2009). However, if images with incremental T2Prep duration are acquired in a sequential fashion, irregular breathing patterns and heart rates may adversely affect the quality of the T2 maps due to misalignment of the source images. A logical alternative is then to acquire all images in an alternating manner (Figure 1ab), where the T2Prep duration changes cyclically from one heartbeat to the next. Combined with a radial signal readout, this may minimize the vulnerability to respiratory or RR variability. We therefore simulated, implemented and tested the utility of an alternating magnetization preparation approach to T2 mapping.
Highlights
T2 mapping through variation of the T2 preparation (T2Prep) duration has been increasingly used to robustly detect and quantify cardiac edema (Giri et al, JCardiovMagnReson2009)
If images with incremental T2Prep duration are acquired in a sequential fashion, irregular breathing patterns and heart rates may adversely affect the quality of the T2 maps due to misalignment of the source images
The alternating sequence was as robust to heart rate variation as its sequential counterpart (Figure 1c), while its accuracy was confirmed in the phantoms (T2 = 45.4 ± 0.7 ms for the alternating method, vs 45.3 ± 0.7 ms for the sequential method and 45.1 ± 0.7 ms for the goldstandard)
Summary
T2 mapping through variation of the T2 preparation (T2Prep) duration has been increasingly used to robustly detect and quantify cardiac edema (Giri et al, JCardiovMagnReson2009). If images with incremental T2Prep duration are acquired in a sequential fashion, irregular breathing patterns and heart rates may adversely affect the quality of the T2 maps due to misalignment of the source images. A logical alternative is to acquire all images in an alternating manner (Figure 1ab), where the T2Prep duration changes cyclically from one heartbeat to the next. Combined with a radial signal readout, this may minimize the vulnerability to respiratory or RR variability. We simulated, implemented and tested the utility of an alternating magnetization preparation approach to T2 mapping
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