Racial differences in breast density on screening digital mammograms comparing R2 quantra volumetric computerized software system vs radiologist birad density measures

Abstract

Breast cancer (BCa) is the second leading cause of death in women. AA women experience a higher death rate, are more likely premenopausal and triple negative. High mammographic breast density (BD) is one of the strongest known risk factors for BCa with a 4-5X increase. High BD is associated with 10% to 29% lower sensitivity in radiologist interpretation. Recent FDA approved R2 Quantra (R2 Q) Hologic volumetric computerized BD software replaces the subjective interpretation with a computerized calculation of density.