Abstract
BackgroundHigh-grade soft tissue sarcoma is rare and associated with poor prognosis. This study examines racial and ethnic variation in presentation and outcomes at a Southeastern US cancer center. MethodsAmong an institutional cohort of patients seen between January 2016–December 2021, racial and ethnic differences were evaluated using chi-squared tests, Kaplan Meier curves, and Cox proportional hazards models. ResultsThere were 295 patients (71 % Non-Hispanic White, 24 % Black, 3 % Hispanic White, 2 % Other). Black representation was greater than national cohorts (24 % vs. 12 %). Histological subtype varied by race/ethnicity (p = 0.007). Adjusting for histology and stage, survival was worse for Black vs. White patients (HR 1.71, 95 % CI 1.07–2.76) and those with metastatic disease (5.47, 3.54–8.44). In non-metastatic patients, survival differences for Black vs. White patients were attenuated by receipt of multi-modal treatment (1.53, 0.82–2.88). ConclusionObserved racial disparities in survival of high-grade sarcoma may be addressed by early, multidisciplinary management.
Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
