Abstract
Rabies neutralizing antibody levels were determined in 143 human serum samples by applying a direct fluorescent-antibody test to BHK-21/S13 cells treated previously with dilutions of the test samples mixed with constant amounts of challenge virus. The results were found to be comparable to those obtained in standard mouse neutralization tests. The described technique, which requires 24 hours for completion, is recommended as an alternative to the time-consuming mouse neutralization test.
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