Abstract
Hepatitis E virus (HEV) has been detected in rabbits, but whether rabbit HEV strains can be transmitted to humans is not known. Of 919 HEV-infected patients in France during 2015–2016, five were infected with a rabbit HEV strain. None of the patients had direct contact with rabbits, suggesting foodborne or waterborne infections.
Highlights
Hepatitis E virus (HEV) has been detected in rabbits, but whether rabbit HEV strains can be transmitted to humans is not known
HEV3 infections are generally asymptomatic and selflimiting, but symptomatic acute hepatitis develops in some patients, mostly older men
Fulminant hepatitis can occur in patients with underlying liver disease, and HEV3 infections can become chronic in immunocompromised patients, such as recipients of solid-organ transplants, persons with hematologic diseases, and patients infected with HIV [2]
Summary
Hepatitis E virus (HEV) has been detected in rabbits, but whether rabbit HEV strains can be transmitted to humans is not known. HEV3 infections are generally asymptomatic and selflimiting, but symptomatic acute hepatitis develops in some patients, mostly older men. The Study The French National Reference Center for HEV (Paris, France) analyzed 919 HEV strains obtained from patients Among the 919 patients, 904 were infected with a genotype 3 strain. One infected patient was immunocompetent and 4 were immunocompromised.
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