Abstract

Amino acid sequence studies were carried out with rabbit light chains from several different sources. Light chain from the specifically purified anti- p-azobenzoate antibody from one rabbit showed a single predominant amino-terminal amino acid sequence Val-Glx-Val-Leu-. This sequence is significantly different from that of rabbit light chains reported by other groups and suggests that this amino-terminal sequence may be that of a new subgroup of rabbit κ light chains. The present amino-terminal sequence is also of particular interest since valine has not been reported as the predominant amino-terminal residues for light chains of any species.

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