Abstract

AbstractQuorum sensing, a bacterial process for coordinating community behavior, has inspired scientists to engineer cell‐cell communication for diverse applications. Fundamental knowledge of the molecular underpinnings of quorum sensing systems enabled engineers to rewire quorum sensing circuits in order to alter quorum sensing processes, program control of bacterial populations, and engineer cell‐cell communication. Further, scientific advancements from diverse engineering disciplines have contributed to the design of devices enabling new modes of manipulating or communicating with biological cells. This perspective reviews early and current developments in engineering cell‐cell communication and its applications. Influence of the quorum sensing field on the authors, both engineers, is briefly discussed.

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