Abstract
Multiple pregnancies are increasing with the progress in Assisted Reproductive Technology. The authors report a case of quintuplet pregnancy after Clomiphene Citrate stimulation. This is a 28-year-old woman, G2, P1 with a 4-year-old child alive, who consulted for maternity desire. She was treated with Clomiphene Citrate at 100 mg daily for five days. The presence of a quintuplet pregnancy at 8 weeks + 5 days was found by ultrasound on 29/12/2018. During the follow up of the pregnancy, she presented pre-eclampsia from 24th week (TA 140/100 mmHg, significant proteinuria, edema of lower limbs). Methyl Dopa treatment was instituted. Tocolytic treatment with Salbumol was prescribed facing uterine contractions at 30 weeks. The patient had premature rupture of membranes at 34 weeks + 4 days, followed by uterine contractions. She had a cesarean section at the same day with the birth of five newborns alive. This is the first reported case in Burkina Faso.
Highlights
The authors report a case of quintuplet pregnancy after Clomiphene Citrate stimulation
This is a 28-year-old woman, G2, P1 with a 4-year-old child alive, who consulted for maternity desire. She was treated with Clomiphene Citrate at 100 mg daily for five days
On 19/06/2018 at 33 weeks + 4 days, she presented a premature rupture of membranes followed by uterine contractions
Summary
Assisted Reproductive Technologies have contributed significantly to increase in the incidence of multiple pregnancies around the word. The risk of perinatal mortality and morbidity is high and often linked to prematurity [1] [3] [4]. This situation is sometimes a difficult problem for parents and obstetricians with the use of reduction techniques to improve the fetal and maternal prognosis [5] [6]. The first case of spontaneous quintuplet pregnancy in Africa was published in 1888 in Dufile in present-day Uganda by A. We report through this article a review of the literature on multiple pregnancies
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