Abstract
We present a case report of a 20-year-old male with diabetes mellitus type 1, who developed severe painful peripheral neuropathy while on the second of a 10-day course with levofloxacin for the treatment of epididymitis. The intensity of the pain rapidly reached scores of 10/10 in a numeric scale 0/10, and the patient was transferred to an inpatient pain unit where he was treated aggressively with minimal improvement. A skin biopsy revealed small fiber neuropathy. Then the patient was treated with intravenous immunoglobulin, which improved the pain. Now the patient is on outpatient intravenous immunoglobulin infusions bimonthly and making a slow recovery.
Highlights
Levofloxacin is an antibiotic utilized to treat several types of bacterial infections including those of the genitourinary tract
Peripheral neuropathy has been included in the Black Box warning on fluoroquinolones by the US Food and Drug Administration (FDA)
We report a case of levofloxacin-induced peripheral neuropathy in a patient with diabetes mellitus type 1
Summary
Levofloxacin is an antibiotic utilized to treat several types of bacterial infections including those of the genitourinary tract. We report a case of levofloxacin-induced peripheral neuropathy in a patient with diabetes mellitus type 1.
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