Abstract

Steroid esters of quinoline and acridine carboxylic acids can undergo template directed delivery of chlorine atoms to a particular steroid hydrogen even though chlorination selectivity studies with 2,3-dimethylbutane suggest that the bonding in the chlorine complex is probably different from that with pyridine templates. Quinoline and acridine esters of 3-alpha-cholestanol undergo template directed steroid chlorination just as pyridine esters do, even though the chlorine atom apparently bonds to the quinoline and acridine systems differently from the three-electron bonds seen with pyridine templates.

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