Abstract
Quinine-Resistant Malaria in Traveler Returning from French Guiana, 2010
Highlights
For P. falciparum malaria acquired in French Guiana, the combination of quinine and doxycycline is one of the first-line recommended treatments (1)
We report quinine treatment failure in a 35-year-old man who was infected during a 3-month stay in Saül, a rural area of French Guiana
The patient sought treatment with fever 4 days after returning to France on June 22, 2010, and a diagnosis of P. falciparum malaria was made on the basis of results of a rapid diagnostic test performed by a private medical laboratory
Summary
Quinine-Resistant Malaria in Traveler Returning from French Guiana, 2010 For P. falciparum malaria acquired in French Guiana, the combination of quinine and doxycycline is one of the first-line recommended treatments (1). An elevated 50% inhibitory concentration (IC50), classified as in vitro quinine resistance, was reported for 17% of 32 P. falciparum isolates obtained during 1983–1987 in French Guiana (3).
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