Abstract
ABSTRACT Although many skin manifestations are isolated to a dermatological disorder, some skin manifestations can be related to a deeper, more systemic issue. The skin is related to other body systems and functions. The importance of being able to recognize these dermatological manifestations and associate them with potential systemic disease can be a critical diagnostic tool for the practitioner. Sometimes, these skin manifestations can be the first sign of an internal disease. Although challenging, recognition, prompt diagnosis, and treatment can alter the course of a life-threatening illness.
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