Abstract
The director of the Institute, Prof. V. I. Burakovsky, noted that the body's response to artificial blood circulation depends on the volume of perfusion, blood oxygen content and saturation, carbon dioxide elimination and anesthesia. The body's reaction to homologous blood is insufficiently studied. It consists mainly in the redistribution of blood, its "sequestration" and violation of microcirculation. With artificial blood circulation lasting 1-1.5 hours with high volumetric perfusion rates and optimal anesthesia, circulatory disorders occur with reversible changes in internal organs. Longer artificial blood circulation causes redistribution of blood, microcirculation disorders, depletion of the adrenal glands, impaired vascular permeability. The adequacy of perfusion should be determined by many indicators (by the reaction of the adrenal glands and vascular system, ECG, EEG data, urine excretion, the state of gas exchange in tissues).
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