Abstract
Epigenetic Alterations In article number 2102226, Young Min Shin, Hak-Joon Sung, and co-workers demonstrate that loading anti-hypoxic microparticles onto glioblastoma (GBM) masses reduces epigenetic drug resistance and suppresses subsequent cell invasiveness. The results are verified using a 3D GBM chip with cell spheres in vitro under media perfusion and in vivo through chip implantation into mouse ischemic hind limbs.
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