Quaternary 2-R-5,6-dihydro-1,2,4-triazolo[3,4-a]isoquinolin-2-ium salts and PEPPSI complexes based thereof

Abstract

Alkylation of substituted 5,6-dihydro-1,2,4-triazolo[3,4-a]isoquinolines with iodomethane, 2-iodopropane, or substituted benzyl halides (R—Hal) afforded quaternary 2-R-5,6-dihydro-1,2,4-triazolo[3,4-a]isoquinolinium salts, for which a possibility of the formation of carbene PEPPSI complexes with palladium(ɪɪ) and pyridine, as well as 2-, 3-, and 4-picolines, was demonstrated.