Abstract
Quantum dots (QDs) have emerged as transformative nanomaterials in drug delivery due to their unique optical and electronic properties, such as tunable fluorescence, high surface area and size-dependent emission in pharmaceutical origin. When integrated with polymers, this hybrid system offers enhanced functionality for targeted, controlled and stimuli-responsive drug delivery. This review focuses on the synthesis and application of quantum dot-polymer composites in drug delivery, emphasizing their ability to improve drug targeting, sustained release and real-time imaging in therapeutic applications. The multifunctionality of these systems enables personalized medicine approaches, particularly in cancer therapy and neurological disorders. Despite their promising potential, concerns related to toxicity and scalability pose significant challenges for their widespread clinical use. Ongoing research efforts are focused on developing more biocompatible QDs, optimizing the design of polymer-QD hybrids and addressing regulatory hurdles. This review, we believe, provides a comprehensive analysis of current advancements in quantum dot-based drug delivery systems and outlines future directions to overcome the existing limitations and enhance clinical applicability. The integration of quantum dots with polymers represents a significant leap forward in the field of nanomedicine, offering the potential for highly efficient, precise and safe drug delivery platforms.
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