Abstract
Quantum enhanced sensitivity in optical tweezers based particle tracking was recently demonstrated. This has provided the necessary tool for quantum metrology to play an important role in biological measurements. Here we introduce the basic theory relevant to such optical tweezers experiments, and overview the significance of sub-shot noise limited sensitivity to practical experiments. In particular, biophysical experiments are subject to optical power constraints, which therefore limits the absolute sensitivity which is classically achievable. Quantum enhanced particle tracking can overcome this limit, and is therefore likely to play an important role in such biophysical experiments in the near future.
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