Abstract
We propose that the DNA within the chromatin behaves as a dynamic combinatorial library capable of forming novel structures by reversible processes. We also hypothesize that states within the library may be linked via quantum tunneling. RNA polymerase then could scan these states and the system decoheres to the “appropriate” state. Two ways of sustaining quantum coherence at relevant time scales could be possible, first, screening: the quantum system can be kept isolated from its decohering environment, second, the existence of decoherence free subspaces .We discuss the role of superconductivity in context of avoiding decoherence in context of our hypothesis.
Highlights
Combinatorial libraries have been extensively used in the pharmaceutical industry to discover novel drug compounds
We propose that the DNA within the chromatin behaves as a dynamic combinatorial library capable of forming novel structures by reversible processes
We propose that states within the library are linked via quantum tunneling
Summary
Combinatorial libraries have been extensively used in the pharmaceutical industry to discover novel drug compounds. A variation on the combinatorial library has been introduced by Ramstrom and Lehn [1] which has been termed as dynamic combinatorial library. This chemistry employs continuous interconversion between the library constituents to generate libraries. Novel structures are continuously generated by reversible chemical reactions which are used for spontaneous assembly and interconversion of building modules. We propose that the DNA within the chromatin behaves as a dynamic combinatorial library capable of forming novel structures by reversible processes. We propose that states within the library are linked via quantum tunneling These states are scanned by RNA polymerase and the system decoheres to the “appropriate” state
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