Abstract
A theoretical mechanism has been proposed for nucleophilic addition of ethylene glycol to 4-hydroxybut-2-ynenitrile on the basis of DFT quantum chemical calculations at the B3LYP/6-311++G(d,p) level of theory. The reaction catalyzed by alkali involves nucleophilic attack by 2-hydroxyethoxide ion on the β-carbon atom of the acetylenic alcohol with intermediate formation of vinylic carbanion which undergoes intramolecular cyclization with closure of 1,3-dioxolane ring.
Full Text 
Sign-in/Register to access full text options
Sign-in/Register to access full text options 
Published version (
Free)
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
