Abstract
Quantitative systems pharmacology (QSP) is an emerging discipline uniting bottom-up approaches from systems biology with top-down approaches from Pharmacometrics. QSP aims to generate highly granular, fit-for-purpose representations of biological systems to study questions arising along the value chain from early drug discovery & development to therapeutic use of (new) drugs. This review articles gives an introduction into the field of QSP and highlights recent developments and advancements. In particular, a focus is laid on new research in QSP methodology as well as on research fields and therapeutic areas in which increased research activities were observed, i.e. pharmacokinetics and drug safety, cardiovascular diseases, central-nervous systems disorders and infectious diseases.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
