Abstract

The quantitative relationship between the structure of 46 O-aryl O-ethyl N-isopropylphosphoramidothioates and their herbicidal activity on the barnyard grass, Echinochloa cruss-galli, was analyzed using physicochemical parameters of the aryl substituents and regression analysis. We found that the hydrophobicity of the whole molecule and the position-specific steric and hydrophobic effects of substituents are important to the activity.

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