Abstract
The larvicidal activity of a number of substituted benzoylphenylureas was measured against the silkworm, Bombyx mori, and the common cutworm, Spodoptera litura, under various synergistic conditions. The effects of substituents at the anilide moiety on the activity were analyzed quantitatively using physicochemical parameters and regression analysis, and compared with those on the activity against the rice stem borer, Chilo suppressalis, analyzed previously. The effects of structural variations at the benzoyl moiety were also quantitatively compared among activities against these insect species. The results indicated that the effects of substituents at the benzoyl moiety are much the same, but the electronic substituent effect at the anilide moiety is quite different among species, being attributable to differences in the participation of the metabolic transformation in the apparent activity. The specific larvicidal spectra of certain compounds in this series were suggested to be due to innate differences in the metabolic mechanism besides differences in the physicochemical substituent effects on the ultimate activity.
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