Quantitative responses of normal alkanes in gas chromatographic—mass spectrometric analysis

Abstract

The quantitative response factors (RF) of fourteen long-chain normal alkanes were determined for gas chromatography—mass spectrometry with electron-impact (GC—EIMS) and chemical ionization (GC—CIMS). IN GC—EIMS analysis, the compounds tested gave very similar RF/unit weight (RF/W) to the total ion current (TIC) and to the mass chromatograms of some characteristics fragment ions. In the GC—CIMS analysis, the alkanes showed similar RF/mol (RF/M) to TIC. However, an average RF/M for the quantitation of a large number of compounds using GC—CIMS could not be developed because of the considerable variations involved.