Abstract

This paper examines the phytochemical constituents and antimicrobial efficacies of n-butanol stem bark fraction of Detarium microcarpum using an in vitro model. The results revealed that the N-butanol fraction of Detarium microcarpum stems tested positive for the presence of Alkaloids, Saponins, Tannins, Flavonoids, Anthraquinones, steroids, and Glycosides. Similarly, the in vitro antimicrobial study also revealed that the n-butanol fraction has effectively inhibited the growth of test organism’s pathogens (Protius, Bacillus subtilis, staphylococaccus aureus, Enterobacta, Eschericia coli, Shigelia dysenteriae, Salmonella typhi, Pseudomonas aeruginosa, Aspergillus nigger. Aspergillus flavus, Candida albicans, Rhezome). The minimum Inhibitory Concentration (MIC). Range from 1.0×104 to 4.0×104. Keywords: Phytochemical Analysis, Antimicrobial Activity, Detarium microcarpum, n-Butanol Fraction, Minimum Inhibitory Concentration (MIC)

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