Quantitative measures of the medial meniscus are associated with progression of knee osteoarthritis - data from the fnih biomarker study

Abstract

Purpose: Menisci are important fibrocartilage structures that protect the articular cartilage during joint mobility and help distributing mechanical load in the joint. Meniscal tears and extrusion, as scored semi-quantitatively by expert radiologists, have been shown to predict and be associated with clinical and structural progression of knee osteoarthritis (KOA). More recently, MRI-based quantitative measurement technology has been developed to determine the 3D position and size of the menisci, including tibial coverage by the meniscus.