Abstract
Modifications of the procedure of Malmstrom and Glick for the micro measurement of coenzyme A were employed in a study of the quantitative histological distribution of the coenzyme in adrenal glands of male albino rats. Subcutaneous injection of 25 mg. ACTH per kg. 3 hours before sacrifice produced significant increases in coenzyme A concentration in the adjoining zones between the glomerulosa and fasciculata, and the fasciculata and reticularis. Small increases occurred in the medulla and the reticular-medullary border zone. Subcutaneous injection of 5 mg. calcium-d-pantothenate 3 hours before sacrifice increased the coenzyme concentration in all zones except the adjacent fascicular-reticular regions. Analysis of whole gland homogenates prepared from adrenals of animals killed at noon and at midnight revealed that the coenzyme concentration was about 100 per cent greater in the latter. Injection of ACTH abolished day-night differences by producing maximal concentrations in both groups. Injection of panto...
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
