Quantitative gait analysis of idiopathic normal pressure hydrocephalus using deep learning algorithms on monocular videos

Sungmoon Jeong,Hosang Yu,Kyunghun Kang,Jaechan Park

doi:10.1038/s41598-021-90524-9

Abstract

A vision-based gait analysis method using monocular videos was proposed to estimate temporo-spatial gait parameters by leveraging deep learning algorithms. This study aimed to validate vision-based gait analysis using GAITRite as the reference system and analyze relationships between Frontal Assessment Battery (FAB) scores and gait variability measured by vision-based gait analysis in idiopathic normal pressure hydrocephalus (INPH) patients. Gait data from 46 patients were simultaneously collected from the vision-based system utilizing deep learning algorithms and the GAITRite system. There was a strong correlation in 11 gait parameters between our vision-based gait analysis method and the GAITRite gait analysis system. Our results also demonstrated excellent agreement between the two measurement systems for all parameters except stride time variability after the cerebrospinal fluid tap test. Our data showed that stride time and stride length variability measured by the vision-based gait analysis system were correlated with FAB scores. Vision-based gait analysis utilizing deep learning algorithms can provide comparable data to GAITRite when assessing gait dysfunction in INPH. Frontal lobe functions may be associated with gait variability measurements using vision-based gait analysis for INPH patients.

Highlights

A vision-based gait analysis method using monocular videos was proposed to estimate temporospatial gait parameters by leveraging deep learning algorithms
This study investigated the validity of a vision-based gait analysis system in idiopathic normal pressure hydrocephalus (INPH) patients using artificial intelligence algorithms for monocular videos in comparison to a well-established gait analysis system
There was a strong correlation in 11 gait parameters between our vision-based gait analysis method and the GAITRite gait analysis system

Summary

Introduction

A vision-based gait analysis method using monocular videos was proposed to estimate temporospatial gait parameters by leveraging deep learning algorithms. Of 563 autopsies presenting dementia neuropathology, only 9 (1.6%) were suspected as INPH1 In spite of this low incidence, diagnosing INPH is important because it is a potentially treatable neurological disorder. A study of Parkinson’s disease patients showed that there was a high correlation in certain gait parameters, such as gait cycle time, stance phase (% of gait cycle time), swing phase (% of gait cycle time), stride length, walking velocity, and cadence, measured by the vision-based gait analysis method and the GAITRite gait analysis s ystem[10]. In our recent study using the GAITRite gait analysis system as a reference system, a vision-based gait analysis method using monocular videos was proposed to properly estimate temporo-spatial gait parameters by leveraging deep learning algorithms[11]. The vision-based gait analysis system can provide clinicians with a low-cost, non-intrusive, and easy-to-use system for quantitative gait analysis[12]

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