Abstract
Background. Represented by physical and mathematical model of cerebral hemodynamics, considered as a flow system. Objective. Development of cerebral blood flow quantification procedure according to scintigraphy data with 99m Tc-HMPAO. Methods. Analytical, numerical and experimental study of the kinetics 99mTc-HMPAO in brain. Results. For the purpose of quantitative assessment of volumetric cerebral blood flow according to the data of scintigraphy with 99m Tc-HMPAO, it was suggested to view the brain as a flow system. This allows calculating volumetric cerebral blood flow after numerical determination of the model parameters according to the results of indirect angiography and establishment of effective blood dilution volume in brain using single-photon emission-computed tomography. In this case, the suggested blood flow calculation procedure does not require any a priori knowledge of hemodynamics in a certain reference area. Conclusions. Preliminary clinical studies allow characterizing the suggested approach to calculation of volumetric cerebral blood flow absolute values as appropriate.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Research Bulletin of the National Technical University of Ukraine "Kyiv Politechnic Institute"
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
