Abstract

The occurrence, development and reperfusion treatment of ischemic stroke may damage the structure and function of the blood-brain barrier, leading to increased permeability of the blood-brain barrier, and then having cerebral edema or hemorrhagic transformation, and finally resulting in poor outcome. Quantitative assessment of blood-brain barrier permeability is now available. This article reviews the assessment methods of blood-brain barrier permeability and their application in patients with ischemic stroke. Key words: Stroke; Brain ischemia; Blood-brain barrier; Permeability; Magnetic resonance imaging; Tomography, X-ray computed

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