Abstract
Platycodi Radix (PR) is the root of Platycodon grandiflorum (Jacq.) A. DC., which has been used for a long time in China to treat pulmonary diseases. The present study aimed to evaluate the quality of PR samples collected from 23 regions of 11 provinces in China. Eight saponins were quantified using HPLC coupled with evaporative light scattering detection (HPLC-ELSD). The samples with the highest total contents of saponins were from southern China, such as Yunnan, Guangxi, Jiangxi, and Guangzhou. The fingerprint analysis of PR samples was conducted by HPLC-UV method. Nineteen common peaks were selected and the similarity values varied from 0.607 to 0.921. These findings indicated that the saponins contents of PR from different regions varied significantly, with PR samples from southern China having the highest contents of saponins. These comprehensive methods were successful in evaluating the quality of PR samples from northern and southern China, which will serve as a guide for the development of PR as a clinical medication.
Highlights
These comprehensive methods were successful in evaluating the quality of Platycodi Radix (PR) samples from northern and southern China, which will serve as a guide for the development of PR as a clinical medication
Platycodi Radix (PR) is the root of Platycodon grandiflorum (Jacq.) A.DC., which has been used for a long time in China to treat pulmonary diseases
In order to evaluate the homogeneity of the quality of PR samples from the different regions of
Summary
Platycodi Radix (PR) is the root of Platycodon grandiflorum (Jacq.) A.DC., which has been used for a long time in China to treat pulmonary diseases. PR is increasingly being used as a traditional herbal medicine, and as a popular functional food due to its rich content of amino acids. It is often made into pickles in Northeast China, Japan, Korea, and other East Asian countries. The starch of PR can be made into high-quality pastry and PR extracts can be used as active ingredients in anti-aging cosmetics and body lotion [1,2,3]. PR is distributed all over China, from the south to the north. In Chinese books of herbal medicine, PR from eastern China was called “Nan jiegeng” and presumed of better quality, while that distributed in north China and northeast
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