Abstract

Voice is the most natural way to express one’s thoughts, but thyroid disease degrades the quality of one’s voice. Thyroid nodules are lumps of thyrocytes in the thyroid gland that may press the voice box, which results in voice change. To visualize the growth in the thyroid gland, the modified 3D Level Set Volumetric Segmentation (3D LSVS) techniques were used. Thyroid nodules’ severity can be measured based on the volume of the lump. An inferential statistic occurs with confidence intervals between the substance of very high concern (SVHC), Systemic Viral Infection (SVI), STMW and SVHD using Multivariate analysis (MVA) and testing. Acoustic analysis measured the voice changes. Different prevalent methods are compared concurrently and the results of quantitative analysis are better.

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