Abstract
We provide a detailed morphometric analysis of eight transmission electron micrographs (TEMs) obtained from the corpus callosum of one cynomolgus macaque. The raw TEM images are included in the article, along with the distributions of the axon caliber and the myelin g-ratio in each image. The distributions are analyzed to determine the relationship between axon caliber and g-ratio, and compared against the aggregate metrics (myelin volume fraction, fiber volume fraction, and the aggregate g-ratio), as defined in the accompanying research article entitled ‘In vivo histology of the myelin g-ratio with magnetic resonance imaging’ (Stikov et al., NeuroImage, 2015).
Highlights
We provide a detailed morphometric analysis of eight transmission electron micrographs (TEMs) obtained from the corpus callosum of one cynomolgus macaque
TIFF Specimen perfusion fixed with 2% paraformaldehyde and 2% glutaraldehyde, stained with osmium Electron microscopy (EM) images were analyzed using an automated method for the segmentation and morphometry of white matter Montreal, Canada Data is included with this article
There is a limited number of publicly available datasets for comprehensive morphometric analysis of white matter microstructure
Summary
The raw TEM images are included in the article, along with the distributions of the axon caliber and the myelin g-ratio in each image. The distributions are analyzed to determine the relationship between axon caliber and g-ratio, and compared against the aggregate metrics (myelin volume fraction, fiber volume fraction, and the aggregate g-ratio), as defined in the accompanying research article entitled ‘In vivo. Histology of the myelin g-ratio with magnetic resonance imaging’ (Stikov et al, NeuroImage, 2015).
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