Abstract

The aim of this study was to propose a quantitative analysis method using technetium (Tc)-99m-labeled red blood cell RBC imaging to allow calculation of the amount and the rate of gastrointestinal (GI) bleeding. Rabbit models of fixed-GI and continuous-GI bleeding were created using catheter infusion. The amount and rate of bleeding were calculated and compared with the infused amount and rate. No significant differences in calculated or actual amounts or rates of GI bleeding were observed after 2, 4, and 6 hours of catheter infusion of Tc-99m-RBCs. The proposed quantitative analysis method using Tc-99m-RBCs GI scintigraphy can accurately calculate the actual amount and rate of GI bleeding.

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