Abstract

AbstractIn this article, after reviewing the different mathematical methods used in quantification we will describe and discuss their respective advantages and inconveniences. First of all, different examples of applications of infrared (IR) spectroscopy, used with or without other analytical chemistry methods, will be presented. Some examples of direct quantitative analysis in food analysis will be reviewed: lipids (measurement of unsaturation degrees, lipids determination), carbohydrates, proteins (secondary structures, quantitative analysis). We will also focus on original examples of the use of IR spectroscopy combined with enzymes.Secondly, some examples of Fourier transform infrared (FTIR) analysis coupled with other analytical methods are reviewed in the following fields: FTIR quantification in pharmaceuticals, petroleum, paints and other industrial products and in the fields of health, environment, and trace compounds analysis.Finally, we will discuss the limitations and perspectives of IR spectroscopy for quantitative analysis. It appears that the most significant developments in the field of quantitative analysis will most probably come through progress in chemometrics and flow analysis (FA) (automation).

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