Abstract

Abstract A stability-indicating reverse phase high-performance liquid chromatography method has been developed to quantify terbutaline sulfate in pharmaceutical dosage forms. The method is accurate and precise with percent relative standard deviations based on 6 readings of 0.6 with an internal standard (salicylic acid) and 0.8 without an internal standard. The results are in excellent agreement with the USP-NF method. A decomposed sample gave 49.4% results with the developed method versus 71.3% with the USP-NF method.

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